Physico-chemical parameters of dianabol stack ensure high efficiency at hypovolemia and shock, as well as when used for therapeutic dilution of blood (hemodilution) due to the normalization of the central and peripheral hemodynamics, microcirculation, improve delivery and oxygen consumption of organs and tissues, normalization of vascular permeability, reduce the local inflammatory response, activation of the immune response, the mobilization of uniform blood cells, saline deposition and their involvement in active metabolism during moderate hemodilution. in addition, the drug improves the rheology of blood and microcirculation, as well as cerebral and feto-placental blood flow by reducing the hematocrit and reduces plasma viscosity decreases platelet aggregation and inhibits the aggregation of erythrocytes.
– Prevention and treatment of hypovolemia and shock during operations, acute blood loss, trauma, infections and burns;
– therapeutic hemodilution.
– Hypersensitivity to the drug (including starch);
– heart failure decompensation;
– Renal failure with oliguria or anuria (creatinine> 2 . mg / dL or, respectively, 177 pM / l)
– pulmonary edema (including cardiogenic)
– intracranial bleeding;
– expressed blood coagulation disorders (including severe bleeding diathesis, anticoagulation)
– hemodialysis ;
– dehydration (if necessary correcting electrolyte metabolism)
– intracranial dianabol stack hypertension.
– compensated chronic heart, liver and kidney failure;
– hemorrhagic diathesis;
– Children under 10 years old;
– Chronic liver disease;
– von Willebrand disease;
Pregnancy and lactation
Although established does not have embryotoxic and teratogenic effects, the use of the drug in the first trimester of pregnancy is contraindicated. In the 2nd and 3rd trimesters of pregnancy may be applied only if the expected benefit to the mother outweighs the potential risk to the fetus.
It is unknown whether in breast milk, therefore caution should be exercised in the appointment of this drug to women during lactation. If necessary, use during lactation should stop breastfeeding.
Dosing and Administration
Dianabol stack administered as an intravenous infusion.
The daily dose and rate of administration depend on the loss of blood the size and value of hematocrit.
Given the possible anaphylactic reactions, the first 10 – 20 ml should be administered slowly and with careful observation of the patient.
The duration treatment depends on the duration and severity of hypovolemia. In applying the drug in order to hemodilution usually operate according to a multi-day therapy regimens.
The daily dose
When the average blood volume replacement dose is usually 250 – 1000 ml. Only in exceptional cases, excess dosage of 20 ml / kg body weight / day. Total of 300 g (5 l) HES treatment should not exceed (at reusable injection).
In applying to hemodilution during several successive days the daily dose is usually 500 ml. The total dose is 5 liters, may be exceeded only in exceptional cases, at the same dose can be distributed for a period of treatment lasting up to four weeks.
The speed of
the absence of an acute emergency, the recommended duration of administration – at least 30 minutes for 500 mL formulation .
Data on the use of children under the age of 10 years are not available, use the drug in this patient group is not recommended.
Anaphylactic reactions to hydroxyethyl starch (based on the entered number of units of infusion solution – about 0.085%). These reactions are in most cases in the form of vomiting, mild fever, chills, pruritus and urticaria. The observed increase in the submandibular and parotid glands, flu-like symptoms (headache, muscle pain, peripheral edema).
The reactions of intolerance, accompanied by shock and life-threatening symptoms (sometimes up to a cardiac arrest and respiratory arrest) extremely rare (based on the entered number of units infusion solution – approximately 0.006%).
When administered in high doses -. increased bleeding
If you have hypersensitive reactions administration should be discontinued immediately. At the same time taking all the necessary emergency measures of assistance (see. Also section “Special Instructions”).
Amylase activity in serum after administration dianabol stack increases markedly, but after 3-5 days back to normal again. The diagnostic or therapeutic measures are required.
Hydroxyethyl starch at its long-term use can cause itching, poorly amenable to cupping, which, under certain conditions, can also appear only at the end of treatment and stay for months.
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